Microneedling is a minimally invasive skin-rejuvenation procedure that involves the use of multiple tiny needles creating microscopic channels in the skin, thus stimulating the skin’s natural healing abilities and collagen production. Most minimally invasive procedures aim to maintain the overlying epidermis while creating dermal injury; therefore, stimulating wound repair and neocollagenesis.
Microneedling, or collagen induction therapy, is a minimally invasive skin rejuvenation procedure that involves the use of a device that contains fine needles. These needles are used to puncture the skin at various depths to create a controlled skin injury. Each puncture creates a channel that stimulates neovascularization and neocollagenesis to fill these microscopic wounds.
The outcomes of microneedling vary based on the device, the depth of needle penetration, frequency of needle penetration, and the number of passes. The needles traumatically create pores in the dermis, which stimulates the release of growth factors and cytokines.
The growth factors and cytokines in turn stimulate collagen, elastin, and neovascularization. Microneedling has shown it initiates collagen synthesis, specifically collagens I, III, and VII. Needling sessions are typically spaced 4 to 6 weeks apart. Microneedling has minimal side effects and can be used safely in patients with all skin types in addition to patients with a history of melasma.
Microneedling should be avoided in patients with a history of keloid or hypertrophic scarring, inflammatory dermatoses, history of herpes simplex virus in perioral area, or any type of growth in the target area. Absolute contraindications for microneedling include scleroderma, collagen vascular disease, clotting disorders, active infection.
3 microneedling sessions in conjunction with PRP at 4 to 6 week intervals saw improvement in newly synthesized collagen, and tropoelastin.